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Biothera Collaborates with USP on Beta-Glucan Monograph

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By: Sean Moloughney

Editor, Nutraceuticals World

The United States Pharmacopeia (USP), in collaboration with Biothera, Eagan, MN, has developed the first official monograph for beta-glucan from bakers yeast (Saccharomyces cerevisiae), a natural food, beverage and dietary supplement ingredient widely recognized for its immune health benefits.

The monograph was recently issued in the Third Supplement of the Seventh Edition of the Food Chemicals Codex, an internationally recognized compendium of standards for the purity and identity of food ingredients.

Biothera manufactures Wellmune WGP, a proprietary bakers yeast beta-glucan shown to prime key immune cells that help keep the body healthy and vital. Biothera contributed the reference standard and two methods for identifying and quantifying the beta 1,3/1,6 branched glucan polymer derived from the cell walls of bakers yeast as well as additional methods to assure the purity of the material.

The Biothera identification method uses Nuclear Magnetic Resonance Spectroscopy to detect glucan branch linkages. To quantify the purity of the beta-glucan content, Biothera developed the Glucan Enzymatic Method (GEM) Assay that was recently published in the ACS Journal of Agricultural and Food Chemistry.

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